Latest Regulations
Good Clinical Practice (GCP) guidelines, ICH E6(R3)
Finalized January 2025
Latest in GCP Compliance: ICH E6(R3) Now Finalized
As of January 2025, the International Council for Harmonisation (ICH) has finalized the updated Good Clinical Practice guideline: ICH E6(R3). This modernized standard reflects the evolving landscape of clinical research and emphasizes data integrity, patient-centricity, and risk-based quality management.
Key Updates to Know:
- Quality by Design: Trials must now proactively identify and manage risks that impact data integrity and participant safety. This approach improves trial design and efficiency.
- Data Integrity & Governance: With the rise of digital trials, E6(R3) prioritizes robust data management throughout the lifecycle of a study, including security and traceability.
- Support for Decentralized & Adaptive Trials: E6(R3) accommodates innovation in trial design, encouraging the use of eConsent, remote monitoring, and digital platforms.
- Participant Communication: Transparency is a key principle. Sponsors must now ensure trial results are shared with participants in accessible, non-technical language.
Why This Matters:
Clinical research sites, sponsors, and CROs must align with these standards to remain compliant, competitive, and ethically sound.
At Altum Health Compliance, we help you:
- Implement risk-based quality systems
- Modernize your SOPs and inspection-readiness plans
- Ensure your trial data meets the highest standards of integrity
- Stay aligned with evolving global regulations
Stay compliant. Stay ahead.
Ready to bring your research operations up to E6(R3) standards?
Contact us today to learn how we can support your site or study.